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Metformin HCl Use In Pregnancy
Metformin Overview
If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Metformin Extended-Release Tablets while you are pregnant. It is not known if Metformin Extended-Release Tablets are found in breast milk. Do not breast-feed while taking Metformin Extended-Release Tablets.
Pregnancy Warnings – Metformin
Metformin has been assigned to pregnancy category B by the FDA. Animal studies have failed to reveal evidence of fetotoxicity. There are no controlled data in human pregnancy. Insulin remains the mainstay of therapy for gestational diabetes due to the close glucose control it affords. Metformin is only recommended for use during pregnancy when benefit outweighs risk.
Warnings Breastfeeding Mother
There are no data on the excretion of metformin into human milk. Metformin is excreted into the milk of rats and achieves milk concentrations comparable to those found in plasma. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
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